内酰胺酶抑制剂复方制剂药代动力学参数表.docx

内酰胺酶抑制剂复方制剂药代动力学参数表药物剂量（g）及用法血峰浓度（gml）清除半衰期（三）蛋白结合率（%）原型药物尿排出率（%）氨莘西林/舒巴坦2/1,iv10915044881/128/3875857585哌拉西林/他嘤巴坦40.5ziv298/340.7-1.20.71.230/3068/80替卡西林/克拉维酸3/0.Iziv324/8.01.1/1.145/2560-70/35-45阿莫西林/克拉维酸0.5/0.Izivl0.2ziv32.2/10.5105.4/28.51.07/1.120.9/0.918/2566.5/46.077.4/63.8头泡哌酮/舒巴坦1/1,ivl0.5zim236.8/130.264.2/19.01.7/170-90/3825/84头抱他咤/阿维巴坦20.5ziv2h90.4/14.62.76/2.71<105.78.2809085头泡洛扎/他嘤巴坦l0.5ziv1h2lziv1h65.7/17.8105/26.4342316-21/30>95>80美罗培南/法硼巴坦2/2,iv3h43.4/55.61.22/1.682/3340-60/75-95亚胺培南-西司他丁/雷利巴坦0.50,50.25ziv.5h104.3V64.01V1.220/40/226377>90